OpenAI releases GPT-Rosalind-6, an AI model for biology that answers more risk questions and is provided only to approved institutions

OpenAI released GPT-Rosalind-6, a model for biology and drug discovery, on October 30; it refuses fewer dual-use risk questions and is provided only to approved organizations, and the company says it will still refuse requests to create biological weapons. The model uses the same weights as GPT-6 Astra, with no new training data or fine-tuning added; what changed is the scope of answers and the access threshold. In a biosecurity knowledge test developed with Gryphon Scientific, GPT-Rosalind-6 refused 9.4% of questions, lower than GPT-6 Astra's 29.2% and higher than version 5.5's 1.8%; OpenAI estimates that, counting refusals as correct answers, the capability score is 85.0%, exceeding the indicative threshold of 80% for high capability, and therefore, under the Preparedness Framework, it maintains the high-capability classification for biological and chemical risk.